JAPAN - For the first time, japanese scientists managed to successfully replace natural teeth in mice by others created from individual cells, tells this week's issue of the journal "Nature Methods." The scientists, coordinated by Takashi Tsuji, used mesenchymal stem cells from bone marrow and epithelial cells, which then turned into a tooth.
First, the scientists promoted the growth of each separate type of cell to obtain larger quantities of them. Then they were injected into a drop of collagen, a substance that the cells in an organism. The cells have grown up to become a tooth with great effectiveness.
When they were implanted in the tooth cavity of a mouse, have developed normally and have been shown to have the same composition and structure as the natural incisors.
According to the authors of the article, the study presents the first evidence of the successful regeneration of an organ through the full deployment of material obtained through bioengineering. For scientists, the search results greatly contribute to the development of bioengineering technologies and the future reconstruction of vital organs in vitro.
Moreover, the findings may encourage the development of organ replacement by regenerative treatment.
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